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1

The origin of the RNA world: Co-evolution of genes and metabolism

Shelley D. Copley, Eric Smith, Harold J. Morowitz

Journal:

Bioorganic Chemistry

Year:

2007

Language:

english

File:

PDF, 188 KB

english, 2007

2

The possibility of alternative microbial life on Earth

Cleland, Carol E., Copley, Shelley D.

Journal:

International Journal of Astrobiology

Year:

2006

Language:

english

File:

PDF, 123 KB

english, 2006

3

Evolution of new enzymes by gene duplication and divergence

Copley, Shelley D.

Journal:

Year:

2020

File:

PDF, 5.02 MB

2020

4

The simplest enzyme revisited: The chicken and egg argument solved

Harold J. Morowitz, Vijaysarathy Srinivasan, Shelley Copley, Eric Smith

Journal:

Year:

2005

Language:

english

File:

PDF, 43 KB

english, 2005

5

Using all the available evidence: perceptions of paediatric occupational therapists about how to increase evidence-based practice

Jodie Copley, Shelley Allen

Journal:

International Journal of Evidence-Based Healthcare

Year:

2009

Language:

english

File:

PDF, 79 KB

english, 2009

6

An evolutionary perspective on protein moonlighting

Copley, Shelley D.

Journal:

Biochemical Society Transactions

Year:

2014

Language:

english

File:

PDF, 432 KB

english, 2014

7

Detection and possible origins of aminomalonic acid in protein hydrolysates

Shelley D. Copley, Elizabeth Frank, Wolff M. Kirsch, Tad H. Koch

Journal:

Analytical Biochemistry

Year:

1992

Language:

english

File:

PDF, 701 KB

english, 1992

8

A simple route for synthesis of 4-phospho-d-erythronate

Yehor Novikov, Shelley D. Copley, Bruce E. Eaton

Journal:

Tetrahedron Letters

Year:

2011

Language:

english

File:

PDF, 164 KB

english, 2011

9

Visualization of protoplast fusion and quantitation of recombination in fused protoplasts of auxotrophic strains of Escherichia coli

MingHua Dai, Sara Ziesman, Thomas Ratcliffe, Ryan T. Gill, Shelley D. Copley

Journal:

Metabolic Engineering

Year:

2005

Language:

english

File:

PDF, 346 KB

english, 2005

10

Diverse mechanistic approaches to difficult chemical transformations: microbial dehalogenation of chlorinated aromatic compounds

Shelley D. Copley

Journal:

Chemistry & Biology

Year:

1997

Language:

english

File:

PDF, 1.26 MB

english, 1997

11

Enzymes with extra talents: moonlighting functions and catalytic promiscuity

Shelley D Copley

Journal:

Current Opinion in Chemical Biology

Year:

2003

Language:

english

File:

PDF, 711 KB

english, 2003

12

Microbial dehalogenases: enzymes recruited to convert xenobiotic substrates

Shelley D Copley

Journal:

Current Opinion in Chemical Biology

Year:

1998

Language:

english

File:

PDF, 732 KB

english, 1998

13

Bacterial sources and sinks of isoprene, a reactive atmospheric hydrocarbon

Ray Fall, Shelley D. Copley

Journal:

Environmental Microbiology

Year:

2000

Language:

english

File:

PDF, 174 KB

english, 2000

14

Identification and localization of a stable sulfenic acid in peroxide-treated tetrachlorohydroquinone dehalogenase using electrospray mass spectrometry

W. Scott Willett, Shelley D. Copley

Journal:

Chemistry & Biology

Year:

1996

Language:

english

File:

PDF, 2.23 MB

english, 1996

15

Evolution of efficient pathways for degradation of anthropogenic chemicals

Copley, Shelley D

Journal:

Nature Chemical Biology

Year:

2009

Language:

english

File:

PDF, 462 KB

english, 2009

16

Moonlighting is mainstream: Paradigm adjustment required

Shelley D. Copley

Journal:

Year:

2012

Language:

english

File:

PDF, 661 KB

english, 2012

17

Evolution of a metabolic pathway for degradation of a toxic xenobiotic: the patchwork approach

Shelley D Copley

Journal:

Trends in Biochemical Sciences

Year:

2000

Language:

english

File:

PDF, 130 KB

english, 2000

18

A Dimethyl Ketal-Protected Benzoin-Based Linker Suitable for Photolytic Release of Unprotected Peptides

Chumachenko, Nataliya, Novikov, Yehor, Shoemaker, Richard K., Copley, Shelley D.

Journal:

Journal of Organic Chemistry

Year:

2011

Language:

english

File:

PDF, 659 KB

english, 2011

19

Divergence of Function in the Thioredoxin Fold Suprafamily: Evidence for Evolution of Peroxiredoxins from a Thioredoxin-like Ancestor†

Copley, Shelley D., Novak, Walter R. P., Babbitt, Patricia C.

Journal:

Year:

2004

Language:

english

File:

PDF, 1.32 MB

english, 2004

20

Genomics of ecology and industrial microbiology

Shelley Copley, Rino Rappuoli

Journal:

Current Opinion in Microbiology

Year:

2009

Language:

english

File:

PDF, 84 KB

english, 2009

21

Why Metabolic Enzymes Are Essential or Nonessential for Growth of Escherichia coli K12 on Glucose †

Kim, Juhan, Copley, Shelley D.

Journal:

Year:

2007

Language:

english

File:

PDF, 351 KB

english, 2007

22

The Orphan Protein Bis-γ-glutamylcystine Reductase Joins the Pyridine Nucleotide Disulfide Reductase Family

Kim, Juhan, Copley, Shelley D.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.63 MB

english, 2013

23

Synthesis of stereoselectively labeled [9-2H,3H]chorismate and the stereochemical course of 5-enolpyruvoylshikimate-3-phosphate synthetase

Grimshaw, Charles E., Sogo, Steven G., Copley, Shelley D., Knowles, Jeremy R.

Journal:

Journal of the American Chemical Society

Year:

1984

Language:

english

File:

PDF, 273 KB

english, 1984

24

MotifCluster: an interactive online tool for clustering and visualizing sequences using shared motifs

Micah Hamady, Jeremy Widmann, Shelley D Copley, Rob Knight

Journal:

Year:

2008

Language:

english

File:

PDF, 4.10 MB

english, 2008

25

Lateral gene transfer and parallel evolution in the history of glutathione biosynthesis genes

Shelley D Copley, Jasvinder K Dhillon

Journal:

Year:

2002

Language:

english

File:

PDF, 969 KB

english, 2002

26

A surprising effect of leaving group on the nucleophilic aromatic substitution reaction catalyzed by 4-chlorobenzoyl CoA dehalogenase

Crooks, Gwen P., Copley, Shelley D.

Journal:

Journal of the American Chemical Society

Year:

1993

Language:

english

File:

PDF, 274 KB

english, 1993

27

CodaChrome: a tool for the visualization of proteome conservation across all fully sequenced bacterial genomes

Rokicki, Joe, Knox, David, Dowell, Robin D, Copley, Shelley D

Journal:

Year:

2014

Language:

english

File:

PDF, 2.00 MB

english, 2014

28

Recruitment of a Double Bond Isomerase To Serve as a Reductive Dehalogenase during Biodegradation of Pentachlorophenol †

Anandarajah, Kandiah, Kiefer, Philip M., Donohoe, Bryon S., Copley, Shelley D.

Journal:

Year:

2000

Language:

english

File:

PDF, 569 KB

english, 2000

29

Multiple Turnovers of the Nicotino-Enzyme PdxB Require α-Keto Acids as Cosubstrates

Rudolph, Johannes, Kim, Juhan, Copley, Shelley D.

Journal:

Year:

2010

Language:

english

File:

PDF, 1.14 MB

english, 2010

30

Exploration of possible mechanisms for 4-chlorobenzoyl CoA dehalogenase: Evidence for an aryl-enzyme intermediate

Crooks, Gwen P., Xu, Ling, Barkley, Robert M., Copley, Shelley D.

Journal:

Journal of the American Chemical Society

Year:

1995

Language:

english

File:

PDF, 1.03 MB

english, 1995

31

The conformational equilibrium of chorismate in solution: implications for the mechanism of the non-enzymic and the enzyme-catalyzed rearrangement of chorismate to prephenate

Copley, Shelley D., Knowles, Jeremy R.

Journal:

Journal of the American Chemical Society

Year:

1987

Language:

english

File:

PDF, 817 KB

english, 1987

32

Purification and Characterization of 4-Chlorobenzoyl CoA Dehalogenase from Arthrobacter sp. Strain 4-CB1

Crooks, Gwen P., Copley, Shelley D.

Journal:

Year:

1994

Language:

english

File:

PDF, 1.08 MB

english, 1994

33

Mechanism of the Severe Inhibition of Tetrachlorohydroquinone Dehalogenase by Its Aromatic Substrates †

Warner, Joseph R., Copley, Shelley D.

Journal:

Year:

2007

Language:

english

File:

PDF, 158 KB

english, 2007

34

The Reaction Catalyzed by Tetrachlorohydroquinone Dehalogenase Does Not Involve Nucleophilic Aromatic Substitution †

Kiefer, Philip M., McCarthy, Darla L., Copley, Shelley D.

Journal:

Year:

2002

Language:

english

File:

PDF, 82 KB

english, 2002

35

A Mechanistic Investigation of the Thiol−Disulfide Exchange Step in the Reductive Dehalogenation Catalyzed by Tetrachlorohydroquinone Dehalogenase †

Warner, Joseph R., Lawson, Sherry L., Copley, Shelley D.

Journal:

Year:

2005

Language:

english

File:

PDF, 121 KB

english, 2005

36

Exploration of the Relationship between Tetrachlorohydroquinone Dehalogenase and the Glutathione S -Transferase Superfamily †

McCarthy, Darla L., Navarrete, Sandra, Willett, W. Scott, Babbitt, Patricia C., Copley, Shelley D.

Journal:

Year:

1996

Language:

english

File:

PDF, 499 KB

english, 1996

37

Evidence That pcpA Encodes 2,6-Dichlorohydroquinone Dioxygenase, the Ring Cleavage Enzyme Required for Pentachlorophenol Degradation in Sphingomonas chlorophenolica Strain ATCC 39723 †

Xu, Ling, Resing, Katheryn, Lawson, Sherry L., Babbitt, Patricia C., Copley, Shelley D.

Journal:

Year:

1999

Language:

english

File:

PDF, 215 KB

english, 1999

38

Pentachlorophenol Hydroxylase, a Poorly Functioning Enzyme Required for Degradation of Pentachlorophenol by Sphingobium chlorophenolicum

Hlouchova, Klara, Rudolph, Johannes, Pietari, Jaana M. H., Behlen, Linda S., Copley, Shelley D.

Journal:

Year:

2012

Language:

english

File:

PDF, 3.44 MB

english, 2012

39

Identification of a Covalent Intermediate between Glutathione and Cysteine13 Formed during Catalysis by Tetrachlorohydroquinone Dehalogenase

McCarthy, Darla L., Louie, Donna F., Copley, Shelley D.

Journal:

Journal of the American Chemical Society

Year:

1997

Language:

english

File:

PDF, 89 KB

english, 1997

40

The mechanism of the chorismate mutase reaction

Guilford, William J., Copley, Shelley D., Knowles, Jeremy R.

Journal:

Journal of the American Chemical Society

Year:

1987

Language:

english

File:

PDF, 970 KB

english, 1987

41

Pre-Steady-State Kinetic Studies of the Reductive Dehalogenation Catalyzed by Tetrachlorohydroquinone Dehalogenase †

Warner, Joseph R., Copley, Shelley D.

Journal:

Year:

2007

Language:

english

File:

PDF, 229 KB

english, 2007

42

A Trade-Off between Catalytic Power and Substrate Inhibition in TCHQ Dehalogenase †

Warner, Joseph R., Behlen, Linda S., Copley, Shelley D.

Journal:

Year:

2008

Language:

english

File:

PDF, 269 KB

english, 2008

43

The uncatalyzed Claisen rearrangement of chorismate to prephenate prefers a transition state of chair-like geometry

Copley, Shelley D., Knowles, Jeremy R.

Journal:

Journal of the American Chemical Society

Year:

1985

Language:

english

File:

PDF, 393 KB

english, 1985

44

Characterization of the Initial Steps in the Reductive Dehalogenation Catalyzed by Tetrachlorohydroquinone Dehalogenase †

Kiefer, Philip M., Copley, Shelley D.

Journal:

Year:

2002

Language:

english

File:

PDF, 92 KB

english, 2002

45

A Radical Intermediate in the Conversion of Pentachlorophenol to Tetrachlorohydroquinone by Sphingobium chlorophenolicum

Rudolph, Johannes, Erbse, Annette H., Behlen, Linda S., Copley, Shelley D.

Journal:

Year:

2014

Language:

english

File:

PDF, 2.29 MB

english, 2014

46

An evolutionary biochemist's perspective on promiscuity

Copley, Shelley D.

Journal:

Trends in Biochemical Sciences

Year:

2015

Language:

english

File:

PDF, 1.40 MB

english, 2015

47

A versatile and highly efficient method for scarless genome editing inEscherichia coliandSalmonella enterica

Kim, Juhan, Webb, Anthony M, Kershner, Jamie P, Blaskowski, Stephen, Copley, Shelley D

Journal:

BMC Biotechnology

Year:

2014

Language:

english

File:

PDF, 1.35 MB

english, 2014

48

Comprehensive Natural Products II || Evolution and the Enzyme

Copley, Shelley D.

Year:

2010

Language:

english

File:

PDF, 2.09 MB

english, 2010

49

A Synonymous Mutation Upstream of the Gene Encoding a Weak-link Enzyme Causes an Ultrasensitive Response in Growth Rate

Kershner, Jamie P., Yu McLoughlin, Sean, Kim, Juhan, Morgenthaler, Andrew, Ebmeier, Christopher C., Old, William M., Copley, Shelley D.

Journal:

Journal of Bacteriology

Year:

2016

Language:

english

File:

PDF, 968 KB

english, 2016

50

Three serendipitous pathways in E. coli can bypass a block in pyridoxal-5′-phosphate synthesis

Kim, Juhan, Kershner, Jamie P, Novikov, Yehor, Shoemaker, Richard K, Copley, Shelley D

Journal:

Molecular Systems Biology

Year:

2010

Language:

english

File:

PDF, 973 KB

english, 2010